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Updated: May 23, 2026

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
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Published on: June 7, 2018

由ATP触发的形状变化划分了GroEL chaperonin的基质结合和折叠机制

Daniel K Clare1, Daven Vasishtan, Scott Stagg

  • 1Crystallography and Institute of Structural and Molecular Biology, Birkbeck College, University of London, Malet Street, London WC1E 7HX, UK.

Cell
|March 27, 2012
PubMed
概括

沙佩罗宁GroEL蛋白与CochaperoninGroES一起使用ATP封装和折叠蛋白质. 显而易见的GroEL-ATP形状揭示了将错误折叠的基板喷射到水友室的机械过程.

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