在早期哺乳动物胚胎中,DNA甲基化的一个独特的调节阶段

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Updated: May 23, 2026

Rapid and Efficient Spatiotemporal Monitoring of Normal and Aberrant Cytosine Methylation within Intact Zebrafish Embryos
07:16

Rapid and Efficient Spatiotemporal Monitoring of Normal and Aberrant Cytosine Methylation within Intact Zebrafish Embryos

Published on: August 18, 2022

Zachary D Smith1, Michelle M Chan, Tarjei S Mikkelsen

  • 1Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.

Nature
|March 30, 2012
PubMed
概括

哺乳动物胚胎发生涉及动态的DNA甲基化变化. 新的基本分辨率地图揭示了早期胚胎中保持着独特的卵细胞衍生甲基化模式,挑战了现有的模型.

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