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中国男性和女性的血清脂质和脂蛋白
Wenying Yang1, Jianzhong Xiao, Zhaojun Yang
1Department of Endocrinology, China-Japan Friendship Hospital, Beijing, China. ywy_1010@yahoo.com.cn
Circulation
|April 12, 2012
概括
高血清胆固醇水平在中国普遍存在.
科学领域:
- 心血管疾病流行病学
- 脂质新陈代谢研究研究
- 在中国的公共卫生.
背景情况:
- 心血管疾病是中国的主要死亡原因,与生活方式的改变有关.
- 估计国家血清脂质和脂蛋白水平对于公共卫生至关重要.
- 了解脂质概况可以为心血管疾病预防策略提供信息.
研究的目的:
- 确定中国成年人口中血清脂质和脂蛋白的全国患病率.
- 为中国各地的胆固醇和甘油三水平提供最新数据.
- 评估目前对高胆固醇的认识,治疗和控制的现状.
主要方法:
- 在全国代表性样本中,对46239名中国成年人 (年龄≥20岁) 进行了横截面研究.
- 测量了禁食血清总胆固醇,高密度脂蛋白胆固醇,低密度脂蛋白胆固醇和甘油三.
- 计算了年龄标准化估计和人口百分比.
主要成果:
- 平均血清总胆固醇为4.72 mmol/L,其中9.0%的总胆固醇高 (≥6.22 mmol/L).
- 平均低密度脂蛋白胆固醇为2.68毫摩尔/升;3.0%的胆固醇水平非常高 (≥4.92毫摩尔/升).
- 22.3%的人患有低高密度脂蛋白胆固醇 (<1.04 mmol/L),高胆固醇的意识/治疗/控制低 (11.0%/5.1%/2.8%).
结论:
- 血清总胆固醇和低密度脂蛋白胆固醇水平在中国很高,并且在增加.
- 对于失脂症的低意识,治疗和控制率构成了重大的公共卫生挑战.
- 如果没有有效的干预措施,动脉样硬化心血管疾病预计将大幅增加.
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