直接观察同位体血红蛋白的合作蛋白结构动力学从100ps到10ms与探针X射线溶液散射

Kyung Hwan Kim1, Srinivasan Muniyappan, Key Young Oang

  • 1Center for Time-Resolved Diffraction, Department of Chemistry, Graduate School of Nanoscience & Technology (WCU), KAIST, Daejeon, 305-701, Republic of Korea.

概括

这项研究使用X射线溶液散射揭示了实时蛋白质结构动态,识别了血红蛋白转换中的三种中间体. 在一个子单元中的联体结合反映了结合在两者的效果,为蛋白质功能提供了新的见解.

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