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零星的自闭症外体揭示了一个高度相互连接的新突变的蛋白质网络

Brian J O'Roak1, Laura Vives, Santhosh Girirajan

  • 1Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington 98195, USA.

Nature
|April 13, 2012
PubMed
概括

De novo突变,通常是父性,与自闭症谱系障碍 (ASD) 风险有关,特别是随着父亲年龄的增加. 破坏性突变准关键基因网络,为ASD提供新的诊断和治疗途径.

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