磁共振成像与左心室重塑的3维分析在孤立的 mitrale 吐:影响超越维度的意义
Chun G Schiros1, Louis J Dell'Italia, James D Gladden
1Samuel Ginn College of Engineering, Department of Electrical and Computer Engineering, Auburn University, Auburn, AL, USA.
Circulation
|April 13, 2012
概括
伴心回 (MR) 患者表现出显著的左心室 (LV) 改造,并未通过标准测量检测到. 这种重塑影响了手术后的LV体积和功能,这表明体积分析对于评估疾病进展至关重要.
科学领域:
- 心血管成像 - 心血管成像
- 心脏外科手术 心脏外科手术
- 心脏衰竭研究研究
背景情况:
- 甲骨管吐 (MR) 手术适用于LV末缩尺寸>40毫米.
- 标准心声回声可能无法完全捕捉MR患者的左心室 (LV) 重塑.
- 中心门手术后,LV射出分数可能会下降.
研究的目的:
- 调查标准心声回声学参数是否反映了MR患者显著的LV重塑.
- 为了比较使用磁共振成像 (MRI) 与标准计算的LV重塑和体积.
- 评估LV改造对术后LV功能的影响.
主要方法:
- 94名MRI患者和51名对照患者接受了电影MRI,包括组织标记和3D分析.
- 组之间的LV末缩体积 (LVESV) 和维度关系的比较.
- 评估了LV喷射分数和缩短前和后米特拉修复手术.
主要成果:
- 在MR患者中,LVESV和LVES维度之间呈现出立方关系,与对照组的二次关系不同.
- 在MR患者中,MRI衍生的LVESV显著高于Bullet配方LVESV,这是由于远端重塑.
- 手术后,LV射出分数和最大缩短显著下降;远端LV重塑持续.
结论:
- 核磁共振症患者显示显著的中至角LV重塑,导致LVESV高于标准几何学预测的水平.
- 手术后下降的LV菌株表明标准措施的局限性.
- 建议对LV重塑和功能进行体积测量分析,用于单独评估MR疾病进展.
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