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Updated: May 23, 2026

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蛋白质折叠和聚合中的中间状态的结构

Philipp Neudecker1, Paul Robustelli, Andrea Cavalli

  • 1Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

Science (New York, N.Y.)
|April 21, 2012
PubMed
概括

蛋白质错误折叠中间体可以在神经退行性疾病中启动粉样纤维的形成. 这项研究揭示了关键中间体的结构,显示了暴露区域如何推动聚合.

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