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脱离自的线粒体DNA会导致炎症和心力衰竭

Takafumi Oka1, Shungo Hikoso, Osamu Yamaguchi

  • 1Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, Japan.

Nature
|April 27, 2012
PubMed
概括

线粒体DNA逃离自会触发心脏细胞的炎症,导致心力衰竭. 阻止托尔类受体9 (TLR9) 阻止这种炎症反应,并保护心脏免受损伤.

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