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Updated: May 22, 2026

Imaging G-protein Coupled Receptor (GPCR)-mediated Signaling Events that Control Chemotaxis of Dictyostelium Discoideum
09:40

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在GC中,B细胞受体信号转导被高酸酶活性短路

Ashraf M Khalil1, John C Cambier, Mark J Shlomchik

  • 1Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.

Science (New York, N.Y.)
|May 5, 2012
PubMed
概括

大多数生殖中心B细胞通过B细胞受体 (BCR) 不能积极发出信号. 相反,酸酶活动限制了信号传递,SHP-1对生殖中心维护和B细胞选择至关重要.

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