在乌干达的学童中,回声心脏病对风湿性心脏病的查
Andrea Beaton1, Emmy Okello, Peter Lwabi
1Children's National Medical Center, Department of Cardiology, 111 Michigan Ave, Washington, DC 20010, USA. abeaton@cnmc.org
Circulation
|May 26, 2012
概括
乌干达学童的心声扫描查发现1.5%的参与者患有风湿性心脏病 (RHD),较低社会经济群体受影响最多. 这强调了在撒哈拉以南非洲的RHD查方案中需要心声回声学.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 儿科 儿科 儿科
背景情况:
- 撒哈拉以南非洲历史上报告了临床检测的风湿性心脏病 (RHD) 的高发病率.
- 从2006年开始的心声回声学查指南在撒哈拉以南非洲的应用有限.
- 此前该地区的RHD查研究主要是在莫桑比克进行的.
研究的目的:
- 根据2006年世卫组织/国家卫生研究院指南,确定乌干达学童的RHD患病率.
- 在这个人群中确定隐性RHD的危险因素.
- 评估实验室测试在RHD诊断中的有用性.
主要方法:
- 在乌干达坎帕拉,对5006名学童 (5-16岁) 进行随机查,使用听觉和便携式心声回声仪.
- 根据2006年指南,疾病概率的分类为确定的,可能的或可能的.
- 对RHD患病率,危险因素和实验室标记物的分析 (Antistreptolysin O标位).
主要成果:
- 心声扫描检查了97%的符合条件的学生,确定了1.5%的RHD (72/4869).
- 心声扫描检测到RHD病例的数量是听诊病例的三倍 (1.5%对比0.5%).
- 来自较低社会经济群体的儿童表现出较高的RHD患病率 (2.7%对1.4%) 和更先进的疾病.
结论:
- 这项研究是撒哈拉以南非洲最大的单一国家儿童RHD患病率评估之一.
- 支持将心声回声纳入查协议,即使在资源有限的环境中也是如此.
- 较低的社会经济群体被确定为最容易受到RHD影响的人群.
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