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Updated: May 12, 2026

Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats
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FoxO1目标Gpr17激活AgRP神经元以调节食物摄入量

Hongxia Ren1, Ian J Orozco, Ya Su

  • 1Berrie Diabetes Center, Department of Medicine, Columbia University, New York, NY 10032, USA.

Cell
|June 12, 2012
PubMed
概括

在Agouti相关 (AgRP) 神经元中抑制FoxO1会减少食物摄入量并促进瘦身. 这一途径涉及G蛋白结合受体Gpr17,为肥胖提供了潜在的治疗点.

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