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通过感知ATP的领先信使RNA控制沙门氏菌毒性位

Eun-Jin Lee1, Eduardo A Groisman

  • 1Howard Hughes Medical Institute, Yale School of Medicine, Section of Microbial Pathogenesis, New Haven, Connecticut 06536-0812, USA.

Nature
|June 16, 2012
PubMed
概括

沙门氏菌细菌通过检测增加的ATP水平来感知酸性环境,从而提高了关键毒性基因 (mgtC) 的表达. 这种ATP感应机制对于沙门氏菌的生存和宿主巨细胞内的毒性至关重要.

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