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减肥手术前后的酒精使用障碍的患病率
Wendy C King1, Jia-Yuh Chen, James E Mitchell
1Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA. kingw@edc.pitt.edu
JAMA
|June 20, 2012
概括
减肥手术并没有立即增加酒精使用障碍 (AUD) 风险,但在第二年患病率上升. 男性的性别,年轻的年龄和某些手术前的因素预测AUD风险在手术后更高.
科学领域:
- 腹部外科手术的结果
- 成 药物 药物 药物 药物
- 胃肠病学 胃肠病学
背景情况:
- 事证据表明,减肥手术可能会增加酒精使用障碍 (AUD) 的风险.
- 减肥手术后AUD患病率的前性数据有限.
研究的目的:
- 为了评估AUD在减肥手术前和后的患病率.
- 为了确定术后AUD的预测因素.
主要方法:
- 对2458名接受减肥手术的成年人进行前性队列研究.
- 在手术后1年和2年使用酒精使用障碍识别测试 (AUDIT) 评估AUD症状.
主要成果:
- 手术前 (7.6%) 和手术后1年 (7.3%) 的AUD症状患病率相似,但在第二年 (9.6%) 显著增加.
- 术后AUD的独立预测因素包括男性性别,年龄较小,吸烟,定期饮酒,之前AUD,娱乐性药物使用,较低的人际支持和Roux-en-Y胃绕道.
结论:
- 在减肥手术后的第二年,AUD的患病率上升.
- 男性的性别,年轻的年龄和特定的术前因素与术后AUD风险增加有关.
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