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Updated: May 21, 2026

Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage
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Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage

Published on: August 21, 2021

特定位置的DICER和DROSHARNA产品控制DNA损伤反应

Sofia Francia1, Flavia Michelini, Alka Saxena

  • 1IFOM Foundation - FIRC Institute of Molecular Oncology Foundation, Via Adamello 16, 20139 Milan, Italy.

Nature
|June 23, 2012
PubMed
概括

DICER 和 DROSHA 酶产生新的小RNA,称为 DDRNA. 这些DDRNA对于激活DNA损伤反应 (DDR) 途径至关重要,揭示了非编码RNA在DNA修复中的新作用.

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Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy08:31

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