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Updated: May 20, 2026

Generation of Centromere-Associated Protein-E CENP-E-/- Knockout Cell Lines using the CRISPR/Cas9 System
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一个可编程的双RNA引导的DNA内核酶在适应性细菌免疫中

Martin Jinek1, Krzysztof Chylinski, Ines Fonfara

  • 1Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA.

Science (New York, N.Y.)
|June 30, 2012
PubMed
概括

CRISPR-Cas9系统使用两个RNA来准和切割特定的DNA序列. 这一发现揭示了RNA可编程基因组编辑技术的新可能性.

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