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Updated: May 20, 2026

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
07:49

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Published on: July 17, 2019

瘤微环境通过HGF分泌引起对RAF抑制剂的先天性耐药性

Ravid Straussman1, Teppei Morikawa, Kevin Shee

  • 1The Eli and Edythe L. Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA.

Nature
|July 6, 2012
PubMed
概括

瘤微环境,而不仅仅是癌细胞,导致耐药性. 流体细胞分泌诸如肝细胞生长因子 (HGF) 等阻断癌症药物有效性的因素,这表明针对癌症和流体细胞的组合疗法.

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