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Updated: May 7, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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NLRP6负面调节天生的免疫力和对细菌病原体的宿主防御

Paras K Anand1, R K Subbarao Malireddi, John R Lukens

  • 1Department of Immunology, St. Jude Children’s Research Hospital, Memphis, Tennessee 38105, USA.

Nature
|July 6, 2012
PubMed
概括

NLRP6负面调节炎症信号,使小鼠抵抗细菌感染,如李斯特菌和大肠杆菌. 它的缺失增强了免疫细胞的激活和细胞因子的产生,这对于病原体清除至关重要.

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