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Updated: May 20, 2026

A Reporter Based Cellular Assay for Monitoring Splicing Efficiency
08:53

A Reporter Based Cellular Assay for Monitoring Splicing Efficiency

Published on: September 15, 2021

U1 snRNP决定了mRNA的长度,并调节了同位体表达的过程

Michael G Berg1, Larry N Singh, Ihab Younis

  • 1Howard Hughes Medical Institute, USA.

Cell
|July 10, 2012
PubMed
概括

U1 snRNP (U1) 保护基因免受过早终止. 适度的U1减少会导致mRNA缩短和外子切换,影响神经元激活和癌症等细胞状态.

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