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可逆切换一个DNA四面体的表面多孔性

Chuan Zhang1, Cheng Tian, Xiang Li

  • 1Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, USA.

Journal of the American Chemical Society
|July 18, 2012
PubMed
概括

研究人员开发了一种具有可切换表面孔的DNA纳米,用于控制运输. 这一突破使药物输送和智能材料的潜在应用成为可能.

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DNA Topoisomerases02:02

DNA Topoisomerases

Topoisomerases are enzymes that relax overwound DNA molecules during various cell processes, including DNA replication and transcription. These enzymes regulate positive and negative DNA supercoiling without changing the nucleotide sequence. DNA overwinding in a clockwise direction results in positively supercoiled DNA, whereas underwinding in a counterclockwise direction produces negatively supercoiled DNA.
Types and Mechanism of action
Topoisomerases are divided into two main types.  Type I...