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静硫氧化酶的动态二硫化物继电器

Assaf Alon1, Iris Grossman, Yair Gat

  • 1Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100, Israel.

Nature
|July 18, 2012
PubMed
概括

酸硫氧化酶 (QSOX) 使用域旋转来在远处的活性位点之间传输二硫化物. 这种结构灵活性解释了其催化机制,并提供了对多域酶设计的见解.

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