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一种具有显著改进的DNA裂变活性的设计型白素

Sheng-Xiong Huang1, Zhiyang Feng, Liyan Wang

  • 1Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, USA.

Journal of the American Chemical Society
|July 27, 2012
PubMed
概括

工程化白色胺素 (BLM) 类似物在癌症治疗方面表现有前途. 新型6'-deoxy-BLM Z表现出强烈的DNA裂变活性,这表明化学疗法可能减少肺毒性.

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