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Updated: May 19, 2026

Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism
11:20

Osmotic Avoidance in Caenorhabditis elegans: Synaptic Function of Two Genes, Orthologues of Human NRXN1 and NLGN1, as Candidates for Autism

Published on: December 11, 2009

在C. elegans中,neurxin和neuroligin通过逆行突触抑制进行介导

Zhitao Hu1, Sabrina Hom, Tambudzai Kudze

  • 1Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.

Science (New York, N.Y.)
|August 4, 2012
PubMed
概括

神经激素 (NRX-1) 和神经激素 (NLG-1) 介导一个逆行信号,控制神经递质释放. 这种信号由微RNA (miR-1) 调节,通过tomosyn.net调整突触囊泡释放动力学.

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Paradigms for Pharmacological Characterization of C. elegans Synaptic Transmission Mutants

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Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors07:51

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors

Published on: November 14, 2014

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Ligand-Gated Ion Channel Receptor: Gating Mechanism01:30

Ligand-Gated Ion Channel Receptor: Gating Mechanism

Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...