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Synthesis and Assay of Vibrio Quorum Sensing Inhibitors
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C4-alkoxy-HPD:一种强大的合成调节器类别,在AI-2定数感应方面超越了自然

Kyoji Tsuchikama1, Jie Zhu, Colin A Lowery

  • 1The Skaggs Institute for Chemical Biology and Department of Chemistry, and Worm Institute for Research and Medicine (WIRM), The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|August 8, 2012
PubMed
概括

研究人员合成了新型化合物,这些化合物作为细菌定数感应 (QS) 的强有力的激动剂. 这些C4-alkoxy-HPDs比Vibrio harveyi中的天然自诱导-2分子更有效地增强信号传输,进步了我们对细菌通信的理解.

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