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Updated: May 19, 2026

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易斯酸催化Mukaiyama aldol反应中的灾难选择性:DFT研究

Joshua M Lee1, Paul Helquist, Olaf Wiest

  • 1Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, USA.

Journal of the American Chemical Society
|August 16, 2012
PubMed
概括

密度函数理论揭示了替代物变化如何影响易斯酸催化Mukaiyama aldol反应中的二元选择性. 特定的过渡结构构造决定了是否有利于亲抗或亲同路径,有助于机理学理解.

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