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乘客删除会在癌症中产生治疗漏洞

Florian L Muller1, Simona Colla, Elisa Aquilanti

  • 1Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

Nature
|August 17, 2012
PubMed
概括

癌细胞中被删除的enolase 1 (ENO1) 基因对以ENO1为向的疗法具有脆弱性. 沉默相关的ENO2基因选择性地抑制这些癌细胞,揭示了潜在的新治疗策略.

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