在Eisenmenger综合征的结果的心声学预测因素
Pamela Moceri1, Konstantinos Dimopoulos, Emmanouil Liodakis
1Adult Congenital Heart Centre and National Centre for Pulmonary Hypertension, Royal Brompton Hospital, London, United Kingdom. moceri.p@chu-nice.fr
Circulation
|August 18, 2012
概括
心声学可以预测艾森门格综合征患者的死亡率. 使用右心室功能和右心房大小的新复合得分显示了评估结果的高准确性.
科学领域:
- 心脏病学 心脏病学
- 肺高血压是什么意思 肺高血压
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 艾森门格综合征在肺动脉高血压管理方面存在独特的挑战.
- 预后和生理差异需要特定的评估工具.
研究的目的:
- 评估艾森门格综合征死亡率的心声波预测因素.
- 开发一种新的风险分层综合评分.
主要方法:
- 181名艾森门格综合征患者 (不包括复杂的先天性心脏病) 接受了心声回声评估.
- 收集后续数据以确定死亡率预测因素.
- 从关键心声学参数中得出一个复合得分.
主要成果:
- 死亡率是由三状环状平面缩外流,心肌性能和右心房大小预测的.
- 一个复合得分 (三环状平面缩外流,RV缩/透缩持续时间比,RA面积,RA/LA面积比) 显示出高的预测准确度 (AUC 0.90).
- 先进的疗法,B型尿酸和氧和没有改善得分的预测能力.
结论:
- 右心室功能和右心房大小的心声测量是艾森门格综合征死亡率的重要预测因素.
- 一个新的复合心声谱评分为定期患者评估和风险分层提供了一种非侵入性方法.
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