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Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice
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肠道炎症针对微生物群的致癌活性

Janelle C Arthur1, Ernesto Perez-Chanona, Marcus Mühlbauer

  • 1Department of Medicine, Pharmacology and Immunology-Microbiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Science (New York, N.Y.)
|August 21, 2012
PubMed
概括

炎症通过改变肠道微生物促进结肠直肠癌 (CRC). 一种特定的细菌,大肠杆菌,携带一种基因毒性岛屿,驱动敏感小鼠的瘤生长,突出了预防CRC的微生物标.

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