相关实验视频

Updated: May 3, 2026

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Published on: January 15, 2022

在心血管风险预测中常见的动脉内心介质厚度测量:一个元分析

Hester M Den Ruijter¹, Sanne A E Peters, Todd J Anderson

¹Julius Center for Health Sciences and Primary Care, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands. hruijte2@umcutrecht.nl

|August 23, 2012

概括

将常见的动脉内膜介质厚度 (CIMT) 添加到弗雷明汉风险评分中,在预测心血管事件方面提供了最小的改善. 这种测量不太可能对10年风险评估具有临床意义.

科学领域:

心血管疾病流行病学
医学成像和诊断医学成像和诊断

背景情况:

关于心血管风险预测模型中常见的动脉内膜介质厚度 (CIMT) 测量的附加值,存在不一致的证据.
现有的风险评分,如弗雷明汉风险评分,旨在预测心血管事件的绝对风险.

研究的目的:

评估是否常见的CIMT测量为超出Framingham风险评分的第一次心肌梗塞或中风的10年风险提供额外的预测价值.
评估将CIMT纳入心血管风险评估中的临床实用性.

主要方法:

在PubMed和EMBASE数据库的系统文献搜索中,补充了专家意见,确定了相关的基于人口的队列.
对45,828名没有先前存在心血管疾病的个人参与者数据进行了元分析.
弗雷明汉风险评分 (Framingham Risk Score) 经过翻新,然后扩展到常见的CIMT,以比较10年风险预测模型.

主要成果:

具有CIMT和没有CIMT的模型的C统计是相似的 (0.757对0.759),表明可比的整体预测能力.
添加共同的CIMT导致所有个体的0.8%的小净重新分类改进.
在中等风险的个体中,净重新分类改善率为3.6%,男性和女性之间没有显著差异.

结论:

常见的CIMT测量的增量值在提高10年心肌梗塞或中风风险预测方面,当添加到Framingham风险评分时,是微不足道的.
观察到的风险预测改善不太可能具有临床意义,质疑CIMT为此目的的常规使用.

更多相关视频

Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome

Published on: September 27, 2024

Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery

Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery

Published on: December 6, 2024

相关概念视频

Assessment of blood pressure in brachial artery(one-step method)

Assessment of blood pressure in brachial artery(one-step method)

This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:

Assessment of blood pressure in brachial artery(two-step method)

Assessment of blood pressure in brachial artery(two-step method)

Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...