在组件中使圆的正方形:从纤维到离散的纳米结构,通过新的设计
Aimee L Boyle1, Elizabeth H C Bromley, Gail J Bartlett
1School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK.
Journal of the American Chemical Society
|August 25, 2012
概括
研究人员设计了可编程,可以自组装成各种生物材料. 这种基于的方法为创建复杂的纳米结构和先进生物材料提供了新的途径.
科学领域:
- 生物材料科学 生物材料科学
- 纳米技术 纳米技术
- 分子生物学分子生物学
背景情况:
- 设计生物启发的纳米结构具有挑战性,通常依赖于DNA自组装.
- 和蛋白质系统在化学多样性,结构,功能和重组生产方面具有优势.
研究的目的:
- 设计和描述可编程自组装成超分子结构的.
- 探索基于的系统作为生物材料建设中DNA的替代品.
主要方法:
- 设计了两个互补的,被编程成一个并行的异构体卷轴.
- 通过可变长度的链接器连接,以创建多样化的超分子组合.
- 从纤维到离散的纳米级对象的特征集.
主要成果:
- 成功创建了一系列基于的组件,包括柔性纤维,体结构和离散的纳米级对象.
- 证明左边长度会影响组装模式,平衡固态和热因素.
- 开发了用于复杂生物材料构建的线性和蛋白质性多.
结论:
- 这项研究提出了一种基于的新策略,用于构建复杂的超分子组件和生物材料.
- 的可编程自组装为先进的材料设计提供了一个多功能平台.
- 基于的系统为DNA创造功能纳米结构提供了一个有希望的替代方案.
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