运动感官投射中的活动揭示了体感觉中的分布式编码
Leopoldo Petreanu1, Diego A Gutnisky, Daniel Huber
1Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia 20147, USA.
Nature
|August 28, 2012
概括
皮层反到体感皮层带有关于胡须运动和触摸的上下文信息. 这使得小鼠能够整合传感数据,以使用主动触摸进行对象定位和导航.
科学领域:
- 神经科学是一个神经科学.
- 感官处理 感官处理
- 皮层电路中的皮层电路.
背景情况:
- 对感官区域的皮层反投影主要针对第1层 (L1).
- 假设L1输入传递上下文信息,但其特定信号没有特征.
- 在动物体感官系统中,振动运动皮质 (vM1) 对振动体感官皮质 (vS1) 的反可以将胡须位置与触摸进行整合,以定位物体.
研究的目的:
- 描述由L1反投影传输的信号,从vM1到vS1.
- 研究这些反信号如何对小鼠的胡须依赖物体定位有所贡献.
主要方法:
- 轴突成像被用于跟踪vM1-->vS1 afferents在L1的 activity.
- 实验是在小鼠执行依赖胡须的物体定位任务时进行的.
主要成果:
- 在L1中的个别轴突代表了胡须的运动,触摸和其他行为特征.
- 一个子集的轴突显示活动取决于物体的位置,持续触摸后.
- 这些发现表明L1反带有集成的感官信息.
结论:
- 桶皮质中的神经元会收到关于胡须运动和触摸的信息.
- 这些综合信息对于通过主动触摸进行对象识别和导航至关重要.
- 对于复杂的行为,L1反在处理上下文感官数据方面发挥着关键作用.
相关概念视频
Somatosensation
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
Motor and Sensory Areas of the Cortex
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Sensory Perception: Organization of the Somatosensory System
The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the stimulus...
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the stimulus...
Overview of Somatic Sensory Pathways
Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
Major Somatic Sensory Pathways
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the posterior columns...
Somatosensory, Motor, and Association Cortex
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at the...


