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哈普托格洛宾-血红蛋白复合体的结构

Christian Brix Folsted Andersen1, Morten Torvund-Jensen, Marianne Jensby Nielsen

  • 1Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark. cbfa@biokemi.au.dk

Nature
|August 28, 2012
PubMed
概括

在血液溶解过程中,哈普特蛋白捕获和中和有害的自由血红蛋白. 晶体结构揭示了哈普托格洛宾如何与血红蛋白结合,保护组织免受氧化损伤,并通过CD163受体促进清除.

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