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Image-guided, Laser-based Fabrication of Vascular-derived Microfluidic Networks
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在复杂的响应性水凝中空间分辨的痕迹扩散.

Swen Lehmann1, Sebastian Seiffert, Walter Richtering

  • 1Institute of Physical Chemistry, RWTH Aachen University, Landoltweg 2, D-52074 Aachen, Germany.

Journal of the American Chemical Society
|September 1, 2012
PubMed
概括
此摘要是机器生成的。

复合水凝与多 (N-异烯胺) 微凝珠显示复杂的行为. 相互透的网络会影响标记器的移动性,并导致不均的胀,从而使生物材料具有可调的透性.

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科学领域:

  • 材料科学 材料科学 材料科学
  • 聚合物科学 聚合物科学
  • 生物材料是一种生物材料.

背景情况:

  • 热敏复合水凝为异质凝提供了模型.
  • 研究了聚烯胺) 水凝矩阵与嵌入的聚烯胺) 微凝珠.
  • 了解复杂的凝环境中的扩散对于生物材料至关重要.

研究的目的:

  • 研究微凝珠和水凝矩阵之间的合.
  • 分析微凝内部相互透网络的形成.
  • 确定复合结构对纳米标记物扩散的影响.

主要方法:

  • 采用了对焦的双焦光相关谱 (2fFCS).
  • 2fFCS被用来研究空间解析的扩散.
  • 监测了德克斯标记物的扩散移动性.

主要成果:

  • 相互透的网络形成取决于微凝交叉链密度.
  • 网络形成阻碍了温度依赖的胀和脱水.
  • 在嵌入式微凝中,德克斯标记剂的移动性受到阻碍.
  • 在加热时观察到聚烯胺基质的不均膨胀.

结论:

  • 复合水凝结构显著影响标记物扩散和胀行为.
  • 定制相互透的网络形成允许调节的水凝特性.
  • 观察到的不均的胀表明有可能创建可调节的透膜.
  • 2fFCS是研究复杂生物材料中的扩散的一个有价值的工具.