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Fun30核细胞重塑器促进了DNA双链断裂端的切除

Xuefeng Chen1, Dandan Cui, Alma Papusha

  • 1Department of Molecular & Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

Nature
|September 11, 2012
PubMed
概括

该研究确定Fun30是重塑染色体的关键酶,通过同源重组促进DNA双链断裂 (DSB) 修复. Fun30通过克服像Rad9.9这样的抑制因素来促进切除过程.

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