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Updated: May 7, 2026

Ascending Aortic Constriction in Rats for Creation of Pressure Overload Cardiac Hypertrophy Model
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在压力过载引起的心脏重塑和心力衰竭时,需要G(13) 介导的信号通路

Mikito Takefuji1, Angela Wirth, Martina Lukasova

  • 1Department of Pharmacology, Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany.

Circulation
|September 14, 2012
PubMed
概括

G 12/13 蛋白家族,特别是 Gα 13 在压力过载引起的心脏重塑和心力衰竭的进展中至关重要. 无活化Gα(13) 保护心脏缩和纤维化.

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