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Updated: May 18, 2026

Genome Editing in Astyanax mexicanus Using Transcription Activator-like Effector Nucleases (TALENs)
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Published on: June 20, 2016

使用高效的TALEN系统进行体内基因组编辑

Victoria M Bedell1, Ying Wang, Jarryd M Campbell

  • 1Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota 55905, USA.

Nature
|September 25, 2012
PubMed
概括

增强的人工转录激活器样效应核酶 (TALEN) 能够在斑马鱼中进行精确的基因组编辑. 这一突破在这个重要的脊椎动物模型中促进了向基因修饰和功能基因组研究.

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