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Procedure for Fabricating Biofunctional Nanofibers
Published on: September 10, 2012
电纳米纤维的组装后衍生通过应变促进的亚酸基因循环添加
Jukuan Zheng1, Kaiyi Liu, Darrell H Reneker
1Department of Polymer Science, The University of Akron, Akron, Ohio 44325, USA.
Journal of the American Chemical Society
|September 28, 2012
概括
一个新的发起者创建了明确定义的聚---L-氨酸) (PBLG) 纳米纤维. 这些纳米纤维成功地与金纳米颗粒功能化,使得组装后易于用于生物活性应用的修改.
科学领域:
- 聚合物化学 聚合物化学
- 纳米技术纳米技术
- 材料科学 材料科学 材料科学
背景情况:
- 开发用于创建功能化的聚合物纳米纤维的方法对于先进的应用至关重要.
- 精确控制聚合物链末端和表面修饰对于量身定制的材料性能至关重要.
研究的目的:
- 通过使用新型启动器,合成明确的聚---L-氨酸) (PBLG) 纳米纤维.
- 为了证明这些纳米纤维与金纳米颗粒的成功组装后功能化.
主要方法:
- 通过一次性氨基衍生物4-二子环氧催醇 (DIBO-PBLG) 启动的环开聚合.
- DIBO-PBLG的电旋转形成纳米纤维.
- 纳米纤维的组装后衍生物化与化物功能化的黄金纳米粒子.
主要成果:
- 成功合成了具有DIBO终端的精确定义的PBLG聚合物.
- 在电后,DIBO末端组保持完整.
- 通过光,SEM和TEM证实了纳米纤维与金纳米颗粒的成功表面功能化.
结论:
- DIBO启动器提供了一个强大的方法来创建可功能化的PBLG纳米纤维.
- 这种方法方便纳米纤维结构与生物活性组的简单的组装后修改.
- 开发的方法有望为各种应用创造先进的纳米材料.
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