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Updated: May 18, 2026

Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry
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超极化的核磁共振用于蛋白质 - 连接体相互作用的表征

Youngbok Lee1, Haifeng Zeng, Simon Ruedisser

  • 1Center for Biological NMR, Department of Chemistry, Texas A&M University, College Station, Texas 77843, USA.

Journal of the American Chemical Society
|October 2, 2012
PubMed
概括

动态核极化增强了的NMR灵敏度,使得低度蛋白质-连接体相互作用的检测成为药物发现的关键. 这种技术可以改善对候选药物的选,即使是那些具有较弱结合亲和力的药物.

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