在做出基于价值的决策的子中,LIP神经元编码提示突出,而不是行动价值
Marvin L Leathers1, Carl R Olson
1Center for the Neural Basis of Cognition, Carnegie Mellon University, Mellon Institute, Room 115, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA. mleathers@cnbc.cmu.edu
概括
侧侧内神经元 (LIP) 信号奖励和处罚,表明对动机突出性的敏感性. 这挑战了LIP神经元仅在决策中编码行动价值的观点.
科学领域:
- 神经科学是一个神经科学.
- 决策研究 决策研究
- 灵长类的认知能力
背景情况:
- 据认为,子中的侧向内神经元 (LIP) 编码了潜在的斜视眼动的值.
- 以前的解释表明,LIP神经元通过与预期的奖励成比例的激发来调解基于价值的决策.
研究的目的:
- 研究LIP神经元在超越奖励价值的决策中的作用.
- 为了确定LIP神经元是否对负面结果 (惩罚) 以及积极结果 (奖励) 敏感.
主要方法:
- 来自子LIP神经元的电生理学记录,子执行一个眼动作任务.
- 操纵与不同saccade目标相关的预期奖励和处罚.
主要成果:
- LIP神经元强烈发射,不仅用于与大奖励相关的冲动,还用于与大惩罚相关的冲动.
- 这表明LIP神经元对线索的动机突出性敏感,反映了潜在的收益和损失.
结论:
- LIP神经元不仅仅代表行动价值;它们参与处理动机突出.
- 这些发现挑战了假设LIP神经元直接介绍基于价值的决策之间的saccades,表明在代表刺激意义的更广泛的作用.
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