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Human Neural Organoids for Studying Brain Cancer and Neurodegenerative Diseases
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由致病性LRRK2引起的人类神经干细胞的渐进性退化

Guang-Hui Liu1, Jing Qu, Keiichiro Suzuki

  • 1National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China. ghliu@ibp.ac.cn

Nature
|October 19, 2012
PubMed
概括

帕金森病与核缺陷有关. 这项研究表明,一种特定的LRRK2突变会导致人类神经干细胞中的核膜问题,影响疾病的进展并提供新的治疗点.

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