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单个神经元测序分析L1逆转换和人体突变在人类大脑中的分析

Gilad D Evrony1, Xuyu Cai, Eunjung Lee

  • 1Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA.

Cell
|October 30, 2012
PubMed
概括

研究了个体大脑神经元中的基因组变异性. 研究人员发现有限的体质LINE-1插入,这表明它们不会显著地推动人类大脑中的神经元多样性.

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Non-LTR Retrotransposons03:18

Non-LTR Retrotransposons

As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...
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