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通过破坏性宏分子抑制剂加速分解IgE受体复合体

Beomkyu Kim1, Alexander Eggel, Svetlana S Tarchevskaya

  • 1Department of Structural Biology, Stanford University School of Medicine, Stanford, California 94305, USA.

Nature
|October 30, 2012
PubMed
概括

一种新型的工程蛋白抑制剂,DARPin E2_79,积极解离预先形成的IgE-FcεRI复合体,提供一种超出传统竞争性抑制的新策略来阻止过敏反应.

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