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Updated: May 17, 2026

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
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用铜催化,用基二甲酸取代二甲酸的反选择性基替代

Yoshinori Shido1, Mika Yoshida, Masahito Tanabe

  • 1Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo, Japan.

Journal of the American Chemical Society
|October 31, 2012
PubMed
概括

这项研究引入了使用基化合物进行的第一个催化酶选择性基替代. 这种新的方法有效地产生带有功能化的基群的奇拉性基,推进非对称合成.

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