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Updated: May 17, 2026

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缺乏Myc增强剂 (包括人类SNP rs6983267) 的小鼠对肠道瘤具有抗性

Inderpreet Kaur Sur1, Outi Hallikas, Anna Vähärautio

  • 1Science for Life Center, Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.

Science (New York, N.Y.)
|November 3, 2012
PubMed
概括

靠近MYC瘤基因的癌症相关遗传变异可以影响癌症风险. 这项研究表明,在小鼠中禁用一个关键的调节元件 (Myc-335) 会对肠道瘤产生抵抗力,证实了这些SNP在体内作用.

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