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感应受体通过Ca2+和cAMP调节NLRP3炎症体

Geun-Shik Lee1, Naeha Subramanian, Andrew I Kim

  • 1Inflammatory Disease Section, Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

Nature
|November 13, 2012
PubMed
概括

感应受体 (CASR) 通过 (Ca2+) 和循环AMP (cAMP) 信号激活NLRP3炎症体. CASR功能障碍有助于导致CAPS等自身炎症性疾病.

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