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Updated: May 16, 2026

Visualization of DNA Repair Proteins Interaction by Immunofluorescence
07:55

Visualization of DNA Repair Proteins Interaction by Immunofluorescence

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修复DNA的支架通过抵消Rad9适配器来抑制检查点信号

Patrice Y Ohouo1, Francisco M Bastos de Oliveira, Yi Liu

  • 1Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York 14853, USA.

Nature
|November 20, 2012
PubMed
概括

DNA修复蛋白Slx4和Rtt107在复制应激过程中防止DNA损伤检查点 (DDC) 的过度激活. 这种调节通过调节Rad53激酶活性来维持基因组稳定性.

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