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Updated: May 16, 2026

In vitro Reconstitution of the Active T. castaneum Telomerase
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In vitro Reconstitution of the Active T. castaneum Telomerase

Published on: July 14, 2011

来自实验衍生约束和建模的Tetrahymena端粒酶RNA的新模型

Daud I Cole1, Jason D Legassie, Laura N Bonifacio

  • 1Department of Biochemistry and Biophysics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.

Journal of the American Chemical Society
|November 21, 2012
PubMed
概括

端粒酶RNA (TER) 在结合端粒酶逆转录酶 (TERT) 时经历了显著的结构变化. 这项研究揭示了自由TER中的新型干III,并模拟了对端粒复制至关重要的TER-TERT相互作用.

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