监管元件的特定站点静音化作为X无活化机制

J Mauro Calabrese1, Wei Sun, Lingyun Song

  • 1Department of Genetics, the Carolina Center for Genome Sciences, and the Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA.

Cell
|November 27, 2012
PubMed
概括

不活跃的X染色体 (Xi) 基因沉默是由特定的调节元素控制的,而不是广泛的染色体范围的变化. 这项研究揭示了Xi转录起点的独特表观遗传特征,影响基因表达和染色质状态.

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