111在左心室血栓塞的血小板成像中. 系统性血栓塞的预测值
1Department of Medicine, Seattle Veterans Administration Medical Center, Washington 98108.
一个阳性111血小板图像表明左心室血栓,表明正在进行的血栓性活动. 这一发现显著预测了与负面图像相比,全身栓塞的风险增加.
科学领域:
- 心脏病学 心脏病学
- 核医学是一种核医学.
- 血栓形成研究研究
背景情况:
- 左心室血栓 (LVT) 形成是心肌梗塞的并发症.
- 评估血栓生成活性对于预测栓塞风险至关重要.
研究的目的:
- 评估是否对LVT的阳性111 (111In) 血小板成像预测了全身栓塞.
- 为了比较阳性和阴性111In血小板图像的患者之间的栓塞率.
主要方法:
- 追溯比较34名患者的血小板图像呈阳性111In,69名患者的血小板图像呈阴性.
- 随访时间平均为38个月,以评估栓塞事件.
- 分析了患者的特征,包括年龄,心脏病发作史,喷射率和治疗方法.
主要成果:
- 血管栓塞事件发生在21%的患者中,呈阳性图像,相对于3%的患者,呈阴性图像 (p=0.002).
- 精算分析显示,86%的正图像患者在42个月后没有栓塞,而98%的负图像患者 (p<0.01).
结论:
- 阳性111 对于LVT的血小板成像是系统性栓塞的显著预测因素.
- 这种成像模式可以识别患有血栓事件风险较高的患者.
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