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优化的末端堆叠为人类端粒G-四重复DNA提供了N-甲基美索氨酸IX的特异性

John M Nicoludis1, Stephen T Miller, Philip D Jeffrey

  • 1Department of Chemistry and Biochemistry, Swarthmore College, 500 College Avenue, Swarthmore, Pennsylvania 19081, United States.

Journal of the American Chemical Society
|November 28, 2012
PubMed
概括

N-甲基中氨酸IX (NMM) 通过调整其形状,融入核心并与离子对齐来选择性地结合并行G-四重复体 (GQ). 这就解释了NMM.

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