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Monitoring Tumor Metastases and Osteolytic Lesions with Bioluminescence and Micro CT Imaging
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在癌症中使用新的基于活动的灭探头对豆素素的功能成像

Laura E Edgington1, Martijn Verdoes, Alberto Ortega

  • 1Cancer Biology Program, Department of Pathology, Stanford School of Medicine, 300 Pasteur Drive, Stanford, California 94305-5324, United States.

Journal of the American Chemical Society
|December 11, 2012
PubMed
概括

研究人员开发了一种光探针来追踪素蛋白质酶 (lysosomal cysteine protease) 的活性. 这种探针有效地标记了癌症和炎症中的豆类蛋白,与巨细胞激活和转移性病变相关联.

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